The Fact About ubat gout yang paling berkesan That No One Is Suggesting
The Fact About ubat gout yang paling berkesan That No One Is Suggesting
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Tanda dan gejala gout hampir selalunya berlaku secara tiba-tiba, dan sering menyerang pada waktu malam. Ia merangkumi:
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Allopurinol adalah salah satu ubat utama dalam terapi penurunan urate (ULT), yang bertujuan untuk mengurangkan pengeluaran asid urik dalam badan. Di Malaysia, allopurinol biasanya dimulakan sekurang-kurangnya empat minggu selepas serangan gout akut untuk mengelakkan keadaan menjadi lebih teruk.
Doktor mungkin menetapkan dos yang lebih tinggi untuk menghentikan serangan akut, diikuti dengan dos harian yang lebih rendah untuk mencegah serangan gout di masa hadapan. Namun begitu, NSAID boleh membawa risiko berlakunya sakit perut, pendarahan dan bisul.
Recommendations propose that ULT be used mostly for Individuals who have two or maybe more gout flare-ups each year or whoever has joint damage brought on by gout. ULT ought to keep on regardless if flare-ups subside.
Various drugs are helpful for acute flare-ups. The effectiveness of very low-dose colchicine is comparable to that of large-dose colchicine with less adverse effects. NSAIDs and glucocorticoids are as helpful as colchicine.
The soreness has a tendency to appear on out of the blue and reaches a peak in 4 to 12 hrs. Even though the initial episode usually resolves in a few days, long term gout attacks are more likely to past lengthier and influence a lot more joints.
Jawapan anda akan membolehkan penilaian keseluruhan click here keadaan anda selama empat minggu terakhir. Sila pilih jawapan yang lebih sesuai dengan keadaan anda.
Pegloticase (Krystexxa) is another choice to reduced manufacture of uric acid. It is normally reserved for people who have significant gout and have not had results with other therapies or are not able to tolerate them. This medication is given intravenously each individual 2 months coupled with weekly oral methotrexate to avoid Negative effects and improve success.
Gout adalah website penyebab yang lazim bagi artritis keradangan (sakit, kemerahan, kepansan dan bengkak pada sendi yang terlibat) dan disebabkan pembentukan kristal-kristal urate sama ada di dalam ataupun di sekeliling sendi-sendi. Asid urik adalah bahan kumuhan yang biasanya dibuang bersama air kencing.
Urate-decreasing therapy is recommended for individuals with two or more gout flare-ups every year, tophaceous gout, or damage attributable to gout noticeable on radiography. Take into consideration beginning therapy for sufferers that has a next flare-up even when not in a person year.
Ketidakselesaan yang berlarutan. Setelah kesakitan yang paling teruk hilang, beberapa ketidakselesaan sendi mungkin berlangsung dari beberapa hari hingga beberapa minggu. Serangan kemudian mungkin akan bertahan lebih lama dan mempengaruhi lebih banyak sendi.
Dalam serangan gout, kristal asid urik yang tajam terkumpul di sekitar sendi, menyebabkan sel imun bertindak balas secara agresif. Reaksi ini menyebabkan keradangan dan sakit.
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